Oh my goodness, a heap of responses that I didn't see, only showed up now! Please ignore my previous comment, except for the bit where I apologise for taking so long to respond! Very grateful to all of you :) I will read this all properly and look up the references, and come back with any further questions :)
In direct response to Prof. Laakso...I hadn't actually made the distinction in my head, but I guess I was considering established scarring.
Again, many thanks :)